Structure of telomerase with telomeric DNA

Telomerase is an RNA-protein complex (RNP) that extends telomeric DNA at the 3’-ends of chromosomes using its telomerase reverse transcriptase (TERT) and integral template-containing telomerase RNA (TER). Its activity is a critical determinant of human health, affecting aging, cancer, and stem cell...

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Bibliografiske detaljer
Udgivet i:Cell
Main Authors: Jiang, Jiansen, Wang, Yaqiang, Sušac, Lukas, Chan, Henry, Basu, Ritwika, Zhou, Z. Hong, Feigon, Juli
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995583/
https://ncbi.nlm.nih.gov/pubmed/29775593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.04.038
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