Efficient lysis of B-chronic lymphocytic leukemia cells by the plant-derived sesquiterpene alcohol α-bisabolol, a dual proapoptotic and antiautophagic agent

The sesquiterpene α-bisabolol (α-BSB) is a cytotoxic agent against acute leukemia and chronic myeloid leukemia cells. Here the profile of α-BSB citotoxicity was evaluated ex vivo in primary mononuclear blood cells isolated from 45 untreated B-chronic lymphocytic leukemia (B-CLL) patients. We studied...

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Vydáno v:Oncotarget
Hlavní autoři: Rigo, Antonella, Ferrarini, Isacco, Bonalumi, Angela, Tecchio, Cristina, Montresor, Alessio, Laudanna, Carlo, Vinante, Fabrizio
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2018
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995246/
https://ncbi.nlm.nih.gov/pubmed/29899828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25398
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