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Role of p27(Kip1) as a transcriptional regulator
The protein p27(Kip1) is a member of the Cip/Kip family of cyclin-dependent kinase (Cdk) inhibitors. It interacts with both the catalytic and the regulatory subunit (cyclin) and introduces a region into the catalytic cleave of the Cdk inducing its inactivation. Its inhibitory capacity can be modulat...
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| Publié dans: | Oncotarget |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Impact Journals LLC
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5995243/ https://ncbi.nlm.nih.gov/pubmed/29899857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25447 |
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