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Potent anti-leukemic activity of a specific cyclin-dependent kinase 9 inhibitor in mouse models of chronic lymphocytic leukemia

Onset of progression even during therapy with novel drugs remains an issue in chronic lymphocytic leukemia (CLL). Thus, there is ongoing demand for novel agents. Approaches targeting cyclin-dependent kinases (CDK) have reached the clinical trial stage. CDK9 mediating RNA transcriptional elongation i...

詳細記述

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書誌詳細
出版年:Oncotarget
主要な著者: Göthert, Joachim R., Imsak, Roze, Möllmann, Michael, Kesper, Stefanie, Göbel, Maria, Dührsen, Ulrich, Scholz, Arne, Lücking, Ulrich, Baumann, Matthias, Unger, Anke, Schultz-Fademrecht, Carsten, Klebl, Bert, Eickhoff, Jan, Choidas, Axel, Dürig, Jan
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995184/
https://ncbi.nlm.nih.gov/pubmed/29899864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25293
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