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Parkinson’s disease: From human genetics to clinical trials

Combining genetic insights into the pathogenesis of Parkinson’s disease (PD) with findings from animal and cellular models of this disorder has advanced our understanding of the pathways that lead to the characteristic degeneration of dopaminergic neurons in the brain’s nigrostriatal pathway. This h...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: van der Brug, Marcel P., Singleton, Andrew, Gasser, Thomas, Lewis, Patrick A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995146/
https://ncbi.nlm.nih.gov/pubmed/26378242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaa8280
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