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Parkinson’s disease: From human genetics to clinical trials

Combining genetic insights into the pathogenesis of Parkinson’s disease (PD) with findings from animal and cellular models of this disorder has advanced our understanding of the pathways that lead to the characteristic degeneration of dopaminergic neurons in the brain’s nigrostriatal pathway. This h...

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Publicado en:Sci Transl Med
Autores principales: van der Brug, Marcel P., Singleton, Andrew, Gasser, Thomas, Lewis, Patrick A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995146/
https://ncbi.nlm.nih.gov/pubmed/26378242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaa8280
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