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Parkinson’s disease: From human genetics to clinical trials

Combining genetic insights into the pathogenesis of Parkinson’s disease (PD) with findings from animal and cellular models of this disorder has advanced our understanding of the pathways that lead to the characteristic degeneration of dopaminergic neurons in the brain’s nigrostriatal pathway. This h...

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Dades bibliogràfiques
Publicat a:Sci Transl Med
Autors principals: van der Brug, Marcel P., Singleton, Andrew, Gasser, Thomas, Lewis, Patrick A.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995146/
https://ncbi.nlm.nih.gov/pubmed/26378242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaa8280
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