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Rev-erbα Dynamically Modulates Chromatin Looping to Control Circadian Gene Transcription
Mammalian physiology exhibits 24-hour cyclicity due to circadian rhythms of gene expression controlled by transcription factors (TF) that comprise molecular clocks. Core clock TFs bind to the genome at enhancer sequences to regulate circadian gene expression, but not all binding sites are equally fu...
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| Pubblicato in: | Science |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5995144/ https://ncbi.nlm.nih.gov/pubmed/29439026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aao6891 |
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