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Rev-erbα Dynamically Modulates Chromatin Looping to Control Circadian Gene Transcription

Mammalian physiology exhibits 24-hour cyclicity due to circadian rhythms of gene expression controlled by transcription factors (TF) that comprise molecular clocks. Core clock TFs bind to the genome at enhancer sequences to regulate circadian gene expression, but not all binding sites are equally fu...

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Bibliografski detalji
Izdano u:Science
Glavni autori: Kim, Yong Hoon, Marhon, Sajid A., Zhang, Yuxiang, Steger, David J., Won, Kyoung-Jae, Lazar, Mitchell A.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995144/
https://ncbi.nlm.nih.gov/pubmed/29439026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aao6891
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