Ca(2+)-activated Cl(−) current is antiarrhythmic by reducing both spatial and temporal heterogeneity of cardiac repolarization

The role of Ca(2+)-activated Cl(−) current (I(Cl(Ca))) in cardiac arrhythmias is still controversial. It can generate delayed afterdepolarizations in Ca(2+)-overloaded cells while in other studies incidence of early afterdepolarization (EAD) was reduced by I(Cl(Ca)). Therefore our goal was to examin...

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Vydáno v:J Mol Cell Cardiol
Hlavní autoři: Hegyi, Bence, Horváth, Balázs, Váczi, Krisztina, Gönczi, Mónika, Kistamás, Kornél, Ruzsnavszky, Ferenc, Veress, Roland, Izu, Leighton T., Chen-Izu, Ye, Bányász, Tamás, Magyar, János, Csernoch, László, Nánási, Péter P., Szentandrássy, Norbert
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995131/
https://ncbi.nlm.nih.gov/pubmed/28668303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2017.06.014
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