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CRISPR base editors: genome editing without double-stranded breaks
The CRISPR (clustered regularly interspaced short palindromic repeat)/Cas9 adaptive immunity system has been harnessed for genome editing applications across eukaryotic species, but major drawbacks, such as the inefficiency of precise base editing and off-target activities, remain. A catalytically i...
Gardado en:
| Publicado en: | Biochem J |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Portland Press Ltd.
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5995079/ https://ncbi.nlm.nih.gov/pubmed/29891532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20170793 |
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