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Binding of serotonin and N(1)-benzenesulfonyltryptamine-related analogs at human 5-HT(6) serotonin receptors: Receptor modeling studies

A population of 100 graphics models of the human 5-HT(6) serotonin receptor was constructed based on the structure of bovine rhodopsin. The endogenous tryptamine-based agonist serotonin (5-HT; 1) and the benzenesulfonyl-containing tryptamine-derived 5-HT(6) receptor antagonist MS-245 (4a) were autom...

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Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Dukat, Małgorzata, Mosier, Philip D., Kolanos, Renata, Roth, Bryan L., Glennon, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5994921/
https://ncbi.nlm.nih.gov/pubmed/18201064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm070910s
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