Chronic constriction injury-induced microRNA-146a-5p alleviates neuropathic pain through suppression of IRAK1/TRAF6 signaling pathway

BACKGROUND: microRNA-146a-5p (miRNA-146a-5p) is a key molecule in the negative regulation pathway of TLRs and IL-1 receptor (TIR) signaling. Our recent study demonstrated that MyD88-dependent signaling pathway of TIR in the dorsal root ganglion (DRG) and spinal dorsal horn (SDH) plays a role in peri...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Wang, Zhiyao, Liu, Fan, Wei, Min, Qiu, Yue, Ma, Chao, Shen, Le, Huang, Yuguang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5994250/
https://ncbi.nlm.nih.gov/pubmed/29885668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1215-4
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