MicroRNA-146a and MicroRNA-146b Regulate Human Dendritic Cell Apoptosis and Cytokine Production by Targeting TRAF6 and IRAK1 Proteins

We have previously reported 27 differentially expressed microRNAs (miRNAs) during human monocyte differentiation into immature dendritic cells (imDCs) and mature DCs (mDCs). However, their roles in DC differentiation and function remain largely elusive. Here, we report that microRNA (miR)-146a and m...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Park, Haein, Huang, Xin, Lu, Changming, Cairo, Mitchell S., Zhou, Xianzheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317016/
https://ncbi.nlm.nih.gov/pubmed/25505246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.591420
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