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Two novel mutations of COMP in Japanese boys with pseudoachondroplasia

Mutations in the cartilage oligomeric matrix protein (COMP) gene cause both pseudoachondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). Most mutations in COMP are located in the region encoding type 3 thrombospondin like domain (TSP3D). We report two Japanese boys with PSACH who had differ...

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Detalhes bibliográficos
Publicado no:Hum Genome Var
Main Authors: Ichihashi, Yosuke, Takagi, Masaki, Ishii, Tomohiro, Watanabe, Kenji, Nishimura, Gen, Hasegawa, Tomonobu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993830/
https://ncbi.nlm.nih.gov/pubmed/29899997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41439-018-0012-z
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