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Osteogenesis imperfecta IIC caused by a novel heterozygous mutation in the C-propeptide region of COL1A1

Osteogenesis imperfecta IIC (OI IIC), which is a rare variant of lethal OI that has been considered to be an autosomal recessive trait, is characterized by twisted, slender long bones with dense metaphyseal margins. Here, we report a typical case of OI IIC caused by a novel heterozygous mutation in...

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Detalhes bibliográficos
Publicado no:Hum Genome Var
Main Authors: Takagi, Masaki, Matsushita, Mitsuru, Nishimura, Gen, Hasegawa, Tomonobu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785516/
https://ncbi.nlm.nih.gov/pubmed/27081514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hgv.2014.25
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