Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation

Macrophage migration inhibitory factor (MIF) exerts multiple effects on immune cells, as well as having functions outside the immune system. MIF can promote inflammation through the induction of other cytokines, including TNF, IL-6, and IL-1 family cytokines. Here, we show that inhibition of MIF reg...

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Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Lang, Tali, Lee, Jacinta P. W., Elgass, Kirstin, Pinar, Anita A., Tate, Michelle D., Aitken, Elizabeth H., Fan, Huapeng, Creed, Sarah J., Deen, Nadia S., Traore, Daouda A. K., Mueller, Ivo, Stanisic, Danielle, Baiwog, Francesca S., Skene, Colin, Wilce, Matthew C. J., Mansell, Ashley, Morand, Eric F., Harris, James
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993818/
https://ncbi.nlm.nih.gov/pubmed/29884801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04581-2
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