The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer’s disease

BACKGROUND: Interleukin-1 beta (IL-1β) and its key regulator, the inflammasome, are suspected to play a role in the neuroinflammation observed in Alzheimer’s disease (AD); no conclusive data are nevertheless available in AD patients. RESULTS: mRNA for inflammasome components (NLRP1, NLRP3, PYCARD, c...

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Veröffentlicht in:Mol Neurodegener
Hauptverfasser: Saresella, Marina, La Rosa, Francesca, Piancone, Federica, Zoppis, Martina, Marventano, Ivana, Calabrese, Elena, Rainone, Veronica, Nemni, Raffaello, Mancuso, Roberta, Clerici, Mario
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778358/
https://ncbi.nlm.nih.gov/pubmed/26939933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-016-0088-1
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