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Herpes simplex virus-1 (HSV-1) infection induces a potent but ineffective IFN-λ production in immune cells of AD and PD patients

BACKGROUND: The sequential activation of immediate early (IE), early (E) and late (L) genes is required to allow productive herpes simplex virus type 1 (HSV-1) infection. Several evidences suggest that, together with inflammation, an immunological response incapable to counteract HSV-1 reactivation...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: La Rosa, Francesca, Agostini, Simone, Bianchi, Anna, Nemni, Raffaello, Piancone, Federica, Marventano, Ivana, Mancuso, Roberta, Saresella, Marina, Clerici, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6712644/
https://ncbi.nlm.nih.gov/pubmed/31455413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-2034-9
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