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Impact of physical confinement on nuclei geometry and cell division dynamics in 3D spheroids

Multicellular tumour spheroids are used as a culture model to reproduce the 3D architecture, proliferation gradient and cell interactions of a tumour micro-domain. However, their 3D characterization at the cell scale remains challenging due to size and cell density issues. In this study, we develope...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Desmaison, Annaïck, Guillaume, Ludivine, Triclin, Sarah, Weiss, Pierre, Ducommun, Bernard, Lobjois, Valérie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993719/
https://ncbi.nlm.nih.gov/pubmed/29884887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27060-6
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