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Characterization of the physical properties of tumor-derived spheroids reveals critical insights for pre-clinical studies

Three-dimensional spheroids are widely used as cancer models to study tumor cell proliferation and to evaluate new anticancer drugs. Growth-induced stress (i.e., stress that persists in tumors after external loads removal) influences tumor growth and resistance to treatment. However, it is not clear...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Guillaume, Ludivine, Rigal, Lise, Fehrenbach, Jérôme, Severac, Childérick, Ducommun, Bernard, Lobjois, Valérie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6488646/
https://ncbi.nlm.nih.gov/pubmed/31036886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43090-0
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