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Oxygen Partial Pressure Is a Rate-Limiting Parameter for Cell Proliferation in 3D Spheroids Grown in Physioxic Culture Condition

The in situ oxygen partial pressure in normal and tumor tissues is in the range of a few percent. Therefore, when studying cell growth in 3D culture systems, it is essential to consider how the physiological oxygen concentration, rather than the one in the ambient air, influences the proliferation p...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Gomes, Aurélie, Guillaume, Ludivine, Grimes, David Robert, Fehrenbach, Jérôme, Lobjois, Valérie, Ducommun, Bernard
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004916/
https://ncbi.nlm.nih.gov/pubmed/27575790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161239
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