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Latch and trigger role for R445 in DAT transport explains molecular basis of DTDS
A recent study reports on five different mutations as sources of Dopamine transporter (DAT) deficiency syndrome (DTDS). One of these mutations, R445C, is believed to be located on the intracellular side of DAT distant to the primary (S1) or secondary (S2) sites to which substrate binding is understo...
Kaydedildi:
| Yayımlandı: | Bioorg Med Chem Lett |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5993566/ https://ncbi.nlm.nih.gov/pubmed/29258773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2017.12.016 |
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