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Optimized dendritic cell vaccination induces potent CD8 T cell responses and anti-tumor effects in transgenic mouse melanoma models

Despite melanoma immunogenicity and remarkable therapeutic effects of negative immune checkpoint inhibitors, a significant fraction of patients does not respond to current treatments. This could be due to limitations in tumor immunogenicity and profound immunosuppression in the melanoma microenviron...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Grees, Mareike, Sharbi-Yunger, Adi, Evangelou, Christos, Baumann, Daniel, Cafri, Gal, Tzehoval, Esther, Eichmüller, Stefan B., Offringa, Rienk, Utikal, Jochen, Eisenbach, Lea, Umansky, Viktor
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993502/
https://ncbi.nlm.nih.gov/pubmed/29900058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1445457
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