mRNA-transfected Dendritic Cells Expressing Polypeptides That Link MHC-I Presentation to Constitutive TLR4 Activation Confer Tumor Immunity

Recently, we have developed a novel genetic platform for improving dendritic cell (DC) induction of peptide-specific CD8 T cells, based on membrane-anchored β(2)-microglobulin (β(2)m) linked to a selected antigenic peptide at its N-terminus and to the cytosolic domain of toll-like receptor (TLR)4 C-...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Cafri, Gal, Sharbi-Yunger, Adi, Tzehoval, Esther, Alteber, Zoya, Gross, Tamar, Vadai, Ezra, Margalit, Alon, Gross, Gideon, Eisenbach, Lea
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817861/
https://ncbi.nlm.nih.gov/pubmed/25997427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.90
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados