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Anti-CTLA-4 based therapy elicits humoral immunity to galectin-3 in patients with metastatic melanoma
The combination of CTLA-4 blockade ipilimumab (Ipi) with VEGF-A blocking antibody bevacizumab (Bev) has demonstrated favorable clinical outcomes in patients with advanced melanoma. Galectin-3 (Gal-3) plays a prominent role in tumor growth, metastasis, angiogenesis, and immune evasion. Here we report...
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| Publicado no: | Oncoimmunology |
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| Principais autores: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5993498/ https://ncbi.nlm.nih.gov/pubmed/29900046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1440930 |
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