Distinct predictive biomarker candidates for response to anti-CTLA-4 and anti-PD-1 immunotherapy in melanoma patients

BACKGROUND: While immune checkpoint blockade has greatly improved clinical outcomes in diseases such as melanoma, there remains a need for predictive biomarkers to determine who will likely benefit most from which therapy. To date, most biomarkers of response have been identified in the tumors thems...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Subrahmanyam, Priyanka B., Dong, Zhiwan, Gusenleitner, Daniel, Giobbie-Hurder, Anita, Severgnini, Mariano, Zhou, Jun, Manos, Michael, Eastman, Lauren M., Maecker, Holden T., Hodi, F. Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840795/
https://ncbi.nlm.nih.gov/pubmed/29510697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-018-0328-8
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