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Basket trial of TRK inhibitors demonstrates efficacy in TRK fusion-positive cancers

Unlike many conventional cancers with preferential patterns of oncogenic genetic alterations, TRK fusions resulting from NTRK1/2/3 genetic alterations drive oncogenic transformations in more than 20 different malignancies over diverse tissue/cell lineages, in both children and adults. A recent “bask...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Chen, Yu, Chi, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992878/
https://ncbi.nlm.nih.gov/pubmed/29880008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-018-0622-4
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