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Saponins as Natural Adjuvant for Antisense Morpholino Oligonucleotides Delivery In Vitro and in mdx Mice

Antisense oligonucleotide (AON) therapy for Duchenne muscular dystrophy has drawn great attention in preclinical and clinical trials, but its therapeutic applications are still limited due to inefficient delivery. In this study, we investigated a few saponins for their potential to improve delivery...

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Podrobná bibliografie
Vydáno v:Mol Ther Nucleic Acids
Hlavní autoři: Wang, Mingxing, Wu, Bo, Shah, Sapana N., Lu, Peijuan, Lu, Qilong
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Gene & Cell Therapy 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992344/
https://ncbi.nlm.nih.gov/pubmed/29858054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.02.004
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