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Saponins as Natural Adjuvant for Antisense Morpholino Oligonucleotides Delivery In Vitro and in mdx Mice

Antisense oligonucleotide (AON) therapy for Duchenne muscular dystrophy has drawn great attention in preclinical and clinical trials, but its therapeutic applications are still limited due to inefficient delivery. In this study, we investigated a few saponins for their potential to improve delivery...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Wang, Mingxing, Wu, Bo, Shah, Sapana N., Lu, Peijuan, Lu, Qilong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992344/
https://ncbi.nlm.nih.gov/pubmed/29858054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.02.004
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