Immunogenicity Testing of Lipidoids In Vitro and In Silico: Modulating Lipidoid-Mediated TLR4 Activation by Nanoparticle Design

Therapeutics based on small interfering RNA (siRNA) have promising potential as antiviral and anti-inflammatory agents. To deliver siRNA across cell membranes to reach the RNAi pathway in the cytosol of target cells, non-viral nanoparticulate delivery approaches are explored. Recently, we showed tha...

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Detaylı Bibliyografya
Yayımlandı:Mol Ther Nucleic Acids
Asıl Yazarlar: de Groot, Anne Marit, Thanki, Kaushik, Gangloff, Monique, Falkenberg, Emily, Zeng, Xianghui, van Bijnen, Djai C.J., van Eden, Willem, Franzyk, Henrik, Nielsen, Hanne M., Broere, Femke, Gay, Nick J., Foged, Camilla, Sijts, Alice J.A.M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Gene & Cell Therapy 2018
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992342/
https://ncbi.nlm.nih.gov/pubmed/29858051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.02.003
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