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miR-16-5p inhibits chordoma cell proliferation, invasion and metastasis by targeting Smad3

Aberrantly expressed miRNAs play a crucial role in the development of multiple cancer types, including chordoma. However, the detailed molecular mechanisms are unclear and need to be elucidated. In this study, miRNAs were screened by miRNA array analysis and then confirmed by real-time PCR analysis....

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Библиографические подробности
Опубликовано в: :Cell Death Dis
Главные авторы: Zhang, Hongliang, Yang, Kang, Ren, Tingting, Huang, Yi, Tang, Xiaodong, Guo, Wei
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992191/
https://ncbi.nlm.nih.gov/pubmed/29880900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0738-z
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