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Downregulation of miR-637 promotes proliferation and metastasis by targeting Smad3 in keloids

Keloids are a type of abnormal scar tissue. MicroRNAs (miRNAs) exhibit a pivotal role in the regulation of cell proliferation and metastasis of keloids. miRNA microarray revealed that miR-637 was one of the most frequently altered miRNAs in keloids. Furthermore, upregulation of miR-637 inhibited cel...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Med Rep
Main Authors: Zhang, Ye, Guo, Bingyu, Hui, Qiang, Li, Wei, Chang, Peng, Tao, Kai
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072149/
https://ncbi.nlm.nih.gov/pubmed/29845237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.9099
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