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miR-16-5p inhibits chordoma cell proliferation, invasion and metastasis by targeting Smad3

Aberrantly expressed miRNAs play a crucial role in the development of multiple cancer types, including chordoma. However, the detailed molecular mechanisms are unclear and need to be elucidated. In this study, miRNAs were screened by miRNA array analysis and then confirmed by real-time PCR analysis....

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Zhang, Hongliang, Yang, Kang, Ren, Tingting, Huang, Yi, Tang, Xiaodong, Guo, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992191/
https://ncbi.nlm.nih.gov/pubmed/29880900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0738-z
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