Pharmacological inactivation of the PI3K p110δ prevents breast tumour progression by targeting cancer cells and macrophages

Patient selection for PI3K-targeted solid cancer treatment was based on the PIK3CA/PTEN mutational status. However, it is increasingly clear that this is not a good predictor of the response of breast cancer cells to the anti-proliferative effect of PI3K inhibitors, indicating that isoform(s) other...

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Bibliografiset tiedot
Julkaisussa:Cell Death Dis
Päätekijät: Goulielmaki, Evangelia, Bermudez-Brito, Miriam, Andreou, Margarita, Tzenaki, Niki, Tzardi, Maria, de Bree, Eelco, Tsentelierou, Eleftheria, Makrigiannakis, Antonis, Papakonstanti, Evangelia A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992183/
https://ncbi.nlm.nih.gov/pubmed/29880805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0717-4
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