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Diffusive tail anchorage determines velocity and force produced by kinesin-14 between crosslinked microtubules

Form and function of the mitotic spindle depend on motor proteins that crosslink microtubules and move them relative to each other. Among these are kinesin-14s, such as Ncd, which interact with one microtubule via their non-processive motor domains and with another via their diffusive tail domains,...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Lüdecke, Annemarie, Seidel, Anja-Maria, Braun, Marcus, Lansky, Zdenek, Diez, Stefan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992172/
https://ncbi.nlm.nih.gov/pubmed/29880831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04656-0
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