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Measuring pushing and braking forces generated by ensembles of kinesin-5 crosslinking two microtubules

The proper organization of the microtubule-based mitotic spindle is proposed to depend on nanometer-sized motor proteins generating forces that scale with a micron-sized geometric feature, such as microtubule overlap length. However, it is unclear if such regulation can be achieved by any mitotic mo...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Shimamoto, Yuta, Forth, Scott, Kapoor, Tarun M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604754/
https://ncbi.nlm.nih.gov/pubmed/26418296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2015.08.017
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