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A Non-Motor Microtubule Binding Site In Kinesin-5 Is Required For Filament Crosslinking And Sliding

Kinesin-5, a widely conserved motor protein required for assembly of the bipolar spindle in vertebrates, forms homotetramers with two pairs of motor domains positioned at opposite ends of a dumbbell shaped molecule [1–3]. It has long been assumed that this configuration of motor domains is the basis...

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Bibliografiset tiedot
Päätekijät: Weinger, Joshua S., Qiu, Minhua, Yang, Ge, Kapoor, Tarun M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049310/
https://ncbi.nlm.nih.gov/pubmed/21236672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.12.038
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