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Novel interaction between Alzheimer’s disease-related protein presenilin 1 and glutamate transporter 1

Neuronal hyperactivity is one of the earliest events observed in Alzheimer’s disease (AD). Moreover, alterations in the expression of glutamate transporters have been reported to exacerbate amyloid pathology and cognitive deficits in transgenic AD mouse models. However, the molecular links between t...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Zoltowska, Katarzyna Marta, Maesako, Masato, Meier, Joshua, Berezovska, Oksana
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992168/
https://ncbi.nlm.nih.gov/pubmed/29880815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26888-2
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