A HILIC-MS/MS Method for Simultaneous Quantification of the Lysosomal Disease Markers Galactosylsphingosine and Glucosylsphingosine in Mouse Serum

Deficiencies of galactosylceramidase and glucocerebrosidase result in the accumulation of galactosylsphingosine (GalSph) and glucosylsphingosine (GluSph) in Krabbe and Gaucher diseases, respectively. GalSph and GluSph are useful biomarkers for both diagnosis and monitoring of treatment effects. We h...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Biomed Chromatogr
Autori principali: Sidhu, Rohini, Mikulka, Christina R., Fujiwara, Hideji, Sands, Mark S., Schaffer, Jean E., Ory, Daniel S., Jiang, Xuntian
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992066/
https://ncbi.nlm.nih.gov/pubmed/29516569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bmc.4235
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi