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Quantification of the anti-influenza drug zanamivir in plasma using high-throughput HILIC–MS/MS

BACKGROUND: Parenteral zanamivir is a promising drug for the treatment of severe influenza. However, quantification of this polar drug in biological matrices has traditionally been difficult and the methods developed have been relatively insensitive. RESULTS: A high-throughput bioanalytical method f...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lindegardh, Niklas, Hanpithakpong, Warunee, Kamanikom, Benjamas, Farrar, Jeremy, Hien, Tran Tinh, Singhasivanon, Pratap, White, Nicholas J, Day, Nicholas P J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096760/
https://ncbi.nlm.nih.gov/pubmed/21250845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/bio.10.189
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