Orally Formulated Artemisinin in Healthy Fasting Vietnamese Male Subjects: A Randomized, Four-Sequence, Open-Label, Pharmacokinetic Crossover Study

BACKGROUND: Artemisinin derivatives are used in antimalarial drug combination therapy. Artemisinin and piperaquine have recently been proven to be prospective candidates for combination therapy in the treatment of uncomplicated Plasmodium falciparum malaria. OBJECTIVE: The goal of this study was to...

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Autores principales: Hien, Tran Tinh, Hanpithakpong, Warunee, Truong, Nguyen Thanh, Dung, Nguyen Thi, Toi, Pham Van, Farrar, Jeremy, Lindegardh, Niklas, Tarning, Joel, Ashton, Michael
Formato: Artigo
Lenguaje:Inglês
Publicado: Excerpta Medica 2011
Materias:
Pharmacokinetics, Bioavailability, & Bioequivalence
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118832/
https://ncbi.nlm.nih.gov/pubmed/21665048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clinthera.2011.04.017
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