Circulating plasmablasts are elevated and produce pathogenic anti-endothelial cell autoantibodies in idiopathic pulmonary arterial hypertension

Idiopathic pulmonary arterial hypertension (IPAH) is a devastating pulmonary vascular disease in which autoimmune and inflammatory phenomena are implicated. B cells and autoantibodies have been associated with IPAH and identified as potential therapeutic targets. However, the specific populations of...

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Udgivet i:Eur J Immunol
Main Authors: Blum, Lisa K., Cao, Richard R.L., Sweatt, Andrew J., Bill, Matthew, Lahey, Lauren J., Hsi, Andrew C., Lee, Casey S., Kongpachith, Sarah, Ju, Chia-Hsin, Mao, Rong, Wong, Heidi H., Nicolls, Mark R., Zamanian, Roham T., Robinson, William H.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992033/
https://ncbi.nlm.nih.gov/pubmed/29369345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201747460
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