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Discovery of Distinct Immune Phenotypes Using Machine Learning in Pulmonary Arterial Hypertension

RATIONALE: Accumulating evidence implicates inflammation in pulmonary arterial hypertension (PAH) and therapies targeting immunity are under investigation, though it remains unknown if distinct immune phenotypes exist. OBJECTIVE: Identify PAH immune phenotypes based on unsupervised analysis of blood...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Sweatt, Andrew J., Hedlin, Haley K., Balasubramanian, Vidhya, Hsi, Andrew, Blum, Lisa K., Robinson, William H., Haddad, Francois, Hickey, Peter M., Condliffe, Robin, Lawrie, Allan, Nicolls, Mark R., Rabinovitch, Marlene, Khatri, Purvesh, Zamanian, Roham T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428071/
https://ncbi.nlm.nih.gov/pubmed/30661465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.118.313911
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