Short Telomeres Induce p53 and Autophagy and Modulate Age-Associated Changes in Cardiac Progenitor Cell Fate

Aging severely limits myocardial repair and regeneration. Delineating the impact of age-associated factors such as short telomeres is critical to enhance the regenerative potential of cardiac progenitor cells (CPCs). We hypothesized that short telomeres activate p53 and induce autophagy to elicit th...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Matsumoto, Collin, Jiang, Yan, Emathinger, Jacqueline, Quijada, Pearl, Nguyen, Nathalie, De La Torre, Andrea, Moshref, Maryam, Nguyen, Jonathan, Levinson, Aimee B., Shin, Minyoung, Sussman, Mark A., Hariharan, Nirmala
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992026/
https://ncbi.nlm.nih.gov/pubmed/29441645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2793
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados