EcoHIV infection of mice establishes latent viral reservoirs in T cells and active viral reservoirs in macrophages that are sufficient for induction of neurocognitive impairment

Suppression of HIV replication by antiretroviral therapy (ART) or host immunity can prevent AIDS but not other HIV-associated conditions including neurocognitive impairment (HIV-NCI). Pathogenesis in HIV-suppressed individuals has been attributed to reservoirs of latent-inducible virus in resting CD...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS Pathog
Päätekijät: Gu, Chao-Jiang, Borjabad, Alejandra, Hadas, Eran, Kelschenbach, Jennifer, Kim, Boe-Hyun, Chao, Wei, Arancio, Ottavio, Suh, Jin, Polsky, Bruce, McMillan, JoEllyn, Edagwa, Benson, Gendelman, Howard E., Potash, Mary Jane, Volsky, David J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2018
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5991655/
https://ncbi.nlm.nih.gov/pubmed/29879225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007061
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