Dynamics of multiple resistance mechanisms in plasma DNA during EGFR‐targeted therapies in non‐small cell lung cancer

Tumour heterogeneity leads to the development of multiple resistance mechanisms during targeted therapies. Identifying the dominant driver(s) is critical for treatment decision. We studied the relative dynamics of multiple oncogenic drivers in longitudinal plasma of 50 EGFR‐mutant non‐small‐cell lun...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Tsui, Dana Wai Yi, Murtaza, Muhammed, Wong, Alvin Seng Cheong, Rueda, Oscar M, Smith, Christopher G, Chandrananda, Dineika, Soo, Ross A, Lim, Hong Liang, Goh, Boon Cher, Caldas, Carlos, Forshew, Tim, Gale, Davina, Liu, Wei, Morris, James, Marass, Francesco, Eisen, Tim, Chin, Tan Min, Rosenfeld, Nitzan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5991591/
https://ncbi.nlm.nih.gov/pubmed/29848757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201707945
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