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The whole transcriptome effects of the PPARα agonist fenofibrate on livers of hepatocyte humanized mice

BACKGROUND: The role of PPARα in gene regulation in mouse liver is well characterized. However, less is known about the role of PPARα in human liver. The aim of the present study was to better characterize the impact of PPARα activation on gene regulation in human liver. To that end, chimeric mice c...

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Bibliografiske detaljer
Udgivet i:BMC Genomics
Main Authors: de la Rosa Rodriguez, Montserrat A., Sugahara, Go, Hooiveld, Guido J. E. J., Ishida, Yuji, Tateno, Chise, Kersten, Sander
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5991453/
https://ncbi.nlm.nih.gov/pubmed/29879903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-4834-3
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