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Lenalidomide enhances the function of CS1 chimeric antigen receptor redirected T cells against multiple myeloma

PURPOSE: Multiple myeloma (MM) remains an incurable malignancy of plasma cells despite considerable advances in treatment. The purpose of the study was to develop novel CARs for the treatment of MM and explore combinatorial therapy using CAR T cells and immunomodulatory drugs such as lenalidomide fo...

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Dettagli Bibliografici
Pubblicato in:Clin Cancer Res
Autori principali: Wang, Xiuli, Walter, Miriam, Urak, Ryan, Weng, Lihong, Huynh, Christian, Lim, Laura, Wong, ChingLam W., Chang, Wen-Chung, Thomas, Sandra, Sanchez, James F., Yang, Lu, Brown, Christine E., Pichiorri, Flavia, Htut, Myo, Krishnan, Amrita, Forman, Stephen J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5991104/
https://ncbi.nlm.nih.gov/pubmed/29061640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-0344
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