Lenalidomide enhances the function of CS1 chimeric antigen receptor redirected T cells against multiple myeloma

PURPOSE: Multiple myeloma (MM) remains an incurable malignancy of plasma cells despite considerable advances in treatment. The purpose of the study was to develop novel CARs for the treatment of MM and explore combinatorial therapy using CAR T cells and immunomodulatory drugs such as lenalidomide fo...

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Bibliografiske detaljer
Udgivet i:Clin Cancer Res
Main Authors: Wang, Xiuli, Walter, Miriam, Urak, Ryan, Weng, Lihong, Huynh, Christian, Lim, Laura, Wong, ChingLam W., Chang, Wen-Chung, Thomas, Sandra, Sanchez, James F., Yang, Lu, Brown, Christine E., Pichiorri, Flavia, Htut, Myo, Krishnan, Amrita, Forman, Stephen J.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5991104/
https://ncbi.nlm.nih.gov/pubmed/29061640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-0344
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