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Dissection of DNA double-strand break repair using novel single-molecule forceps

Repairing DNA double-strand breaks (DSBs) by non-homologous end-joining (NHEJ) requires multiple proteins to recognize and bind DNA ends, process them for compatibility, and ligate them together. We constructed novel DNA substrates for single-molecule nano-manipulation allowing us to mechanically de...

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Publicado no:Nat Struct Mol Biol
Main Authors: Wang, Jing L., Duboc, Camille, Wu, Qian, Ochi, Takashi, Liang, Shikang, Tsutakawa, Susan E., Lees-Miller, Susan P., Nadal, Marc, Tainer, John A., Blundell, Tom L., Strick, Terence R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5990469/
https://ncbi.nlm.nih.gov/pubmed/29786079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-018-0065-1
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