The Hormone FGF21 Stimulates Water Drinking in Response to Ketogenic Diet and Alcohol

Alcohol and ketogenic diets increase water consumption. Here, we show that the hormone FGF21 is required for this drinking response in mice. Circulating levels of FGF21 are increased by alcohol consumption in humans, and by both alcohol and ketogenic diets in mice. Pharmacologic administration of FG...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Song, Parkyong, Zechner, Christoph, Hernandez, Genaro, Cánovas, José, Xie, Yang, Sondhi, Varun, Wagner, Martin, Stadlbauer, Vanessa, Horvath, Angela, Leber, Bettina, Hu, Ming Chang, Moe, Orson W., Mangelsdorf, David J., Kliewer, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5990458/
https://ncbi.nlm.nih.gov/pubmed/29657029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2018.04.001
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